To achieve our mission, we are developing a portfolio of Tumor-Specific Immuno-Gene (T-SIGn®) therapeutics which aim to enable a patient’s own immune system to recognize, attack, and clear their cancer. T-SIGn® therapeutics home specifically to solid tumors following intravenous delivery where they drive expression of therapeutic proteins to remodel the tumor microenvironment and trigger robust antitumor immune responses.
Our T-SIGn® therapeutics are a novel class of medicines with potential for use in the monotherapy setting, as well as in combination with other immuno-oncology agents, to deliver efficacy and offer new hope to people living with difficult-to-treat solid tumors.
A growing pipeline of T-SIGn® therapeutics aiming to enable a patient’s immune system to recognize, attack, and clear solid tumors .
T-SIGn® therapeutics are viral vector based, tumor gene therapies which are capable of homing specifically to primary and metastatic solid tumors following intravenous delivery. Once at the tumor site, T-SIGn® therapeutics can drive intratumoral expression of multiple immunologically active biomolecules and therapeutic proteins to remodel the tumor microenvironment and trigger robust antitumor immune responses.
